Self-hosted alternatives to cobrapy
5 self-hosted AI Skills apps to use instead, best rated first.
Top picks
- C

claude-to-deerflow
Launchclaude-to-deerflow is an agent skill that lets an assistant send messages and questions to a running DeerFlow instance through its HTTP API. DeerFlow is an AI agent platform built on LangGraph that orchestrates sub-agents for research, code
Self-hosted
- O

open-notebook
Launchopen-notebook is an agent skill for organising research with Open Notebook, a self-hosted alternative to NotebookLM. It arranges sources, notes and AI conversations into research notebooks. Sources can be PDFs, web pages, audio, video and O
Self-hosted
- R

Reactive Resume
LaunchReactive Resume is a free and open-source resume builder for writing resumes and cover letters, checking the work, and tracking job applications. You create a free account, import an existing resume or start from scratch, and see the finish
Open sourceSelf-hosted
- S

self-hosted-funnel-launch
LaunchSelf-hosted funnel launch is an agent skill that takes a funnel from an empty install to published on infrastructure you control, using the Autonnel funnel builder, which is licensed Apache-2.0. The result covers a landing page, checkout, a
Self-hosted
- G

get-convex/convex-backend
LaunchConvex is an open-source reactive database for web app developers. It combines a database, a place to write server functions in pure TypeScript, and client libraries that keep the app's data live, so screens update as the data changes. Beca
Self-hosted
About cobrapy

cobrapy
Performs constraint-based metabolic modeling
cobrapy is an agent skill for constraint-based metabolic modelling with COBRApy. It covers loading and building metabolic networks, optimising their steady-state fluxes, and running knockout screens. It also covers medium design, sampling of the feasible flux space and gap-filling hypotheses. The methods named include flux balance analysis, parsimonious FBA, flux variability analysis, gene knockouts, flux sampling, growth media and production envelopes. The skill is careful about what the methods can show. Flux balance analysis is a constraint-based prediction. It does not infer kinetic rates, and it does not establish experimental growth, thermodynamic feasibility or flux identifiability. The skill targets cobra 0.32.1, which is imported as cobra, and it was checked against the released source and current documentation. The install command is uv pip install with cobra pinned to 0.32.1, and an optional extra adds SciPy support for MATLAB file input and output and array operations. It is part of the k-dense-ai scientific agent skills repository on GitHub, which has about 49,600 stars.
- Price
- Free
- Made by
- k-dense-ai
- Category
- AI Skills
- Website
- github.com/k-dense-ai/scientific-agent-skills/cobrapy