Open source alternatives to depmap
24 open source AI Skills apps to use instead, best rated first.
Top picks
- G

github-ops
Launchgithub-ops is an agent skill from the ECC collection by affaan-m, listed on skills.sh. It manages a GitHub repository with a focus on community health, CI reliability and the experience of contributors. It covers triaging issues by classify
Open source
- O

opensource-pipeline
Launchopensource-pipeline is an agent skill from the ECC collection by affaan-m, listed on skills.sh. It prepares a private project for safe public release through a three-stage pipeline. The fork stage strips secrets from a copy. The sanitise st
Open source
- A

andrej-karpathy-skills
Launchandrej-karpathy-skills is a single CLAUDE.md file from the multica-ai project that is meant to improve how Claude Code behaves on coding tasks. It is derived from Andrej Karpathy's public observations about LLM coding pitfalls. The file dis
Open source
- M

microsoft/markitdown
Launchmarkitdown-mcp is the MCP server package for MarkItDown, Microsoft's tool for converting many file formats to Markdown for language models. It is a lightweight server that runs over stdio, Streamable HTTP or SSE, and exposes one tool, conve
Open source
- O

od-contribute
Launchod-contribute is an agent skill in the OpenDesign project that provides a guided, one-click contribution flow to the OpenDesign repository, written so that people without a coding background can send a real pull request. It is locked to the
Open source
- G

github-deep-research
Launchgithub-deep-research is an agent skill from the DeerFlow project that researches a single GitHub repository in several rounds and writes a report in Markdown. It is for requests that need more than a README summary, such as a comprehensive
Open source
More AI Skills apps

modelcontextprotocol/server-memory
Knowledge graph-based persistent memory for maintaining context

netdata/netdata#Netdata
Discovery, exploration, reporting and root cause analysis over Netdata metrics

Learn Claude Code
by shareAI-lab - A really interesting analysis of how coding agents like Claude
About depmap

depmap
Retrieves and analyzes Cancer Dependency Map
depmap is an agent skill for retrieving and analysing Cancer Dependency Map release data. DepMap integrates CRISPR screens from the Broad and Sanger institutes and hosts independent RNAi and drug-screen datasets. The skill covers CRISPR Chronos gene effects, cancer model annotations, omics biomarkers and PRISM compound response. You can use it to rank dependencies in cancer models, compare biomarker cohorts that you have specified in advance, look at co-essentiality, or relate genetic dependencies to compound response. The skill is clear that these analyses generate hypotheses, including target and synthetic-lethality hypotheses, and do not show clinical efficacy, a therapeutic window or a causal interaction. It also explains that RNAi, with DEMETER2, is a different perturbation method rather than an older way of scoring CRISPR data, so each question must be matched to its assay and a pinned release. The skill starts by discovering the current release and obtaining its files from the DepMap downloads page, and it reads the release notes.
- Price
- Free
- Made by
- k-dense-ai
- Category
- AI Skills
- Website
- github.com/k-dense-ai/scientific-agent-skills/depmap











