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depmap

Self-hosted alternatives to depmap

5 self-hosted AI Skills apps to use instead, best rated first.

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About depmap

D

depmap

Retrieves and analyzes Cancer Dependency Map

depmap is an agent skill for retrieving and analysing Cancer Dependency Map release data. DepMap integrates CRISPR screens from the Broad and Sanger institutes and hosts independent RNAi and drug-screen datasets. The skill covers CRISPR Chronos gene effects, cancer model annotations, omics biomarkers and PRISM compound response. You can use it to rank dependencies in cancer models, compare biomarker cohorts that you have specified in advance, look at co-essentiality, or relate genetic dependencies to compound response. The skill is clear that these analyses generate hypotheses, including target and synthetic-lethality hypotheses, and do not show clinical efficacy, a therapeutic window or a causal interaction. It also explains that RNAi, with DEMETER2, is a different perturbation method rather than an older way of scoring CRISPR data, so each question must be matched to its assay and a pinned release. The skill starts by discovering the current release and obtaining its files from the DepMap downloads page, and it reads the release notes.

View depmapAll AI Skills apps
Price
Free
Made by
k-dense-ai
Category
AI Skills
Website
github.com/k-dense-ai/scientific-agent-skills/depmap