Self-hosted alternatives to polars-bio
5 self-hosted AI Skills apps to use instead, best rated first.
Top picks
- C

claude-to-deerflow
Launchclaude-to-deerflow is an agent skill that lets an assistant send messages and questions to a running DeerFlow instance through its HTTP API. DeerFlow is an AI agent platform built on LangGraph that orchestrates sub-agents for research, code
Self-hosted
- O

open-notebook
Launchopen-notebook is an agent skill for organising research with Open Notebook, a self-hosted alternative to NotebookLM. It arranges sources, notes and AI conversations into research notebooks. Sources can be PDFs, web pages, audio, video and O
Self-hosted
- R

Reactive Resume
LaunchReactive Resume is a free and open-source resume builder for writing resumes and cover letters, checking the work, and tracking job applications. You create a free account, import an existing resume or start from scratch, and see the finish
Open sourceSelf-hosted
- S

self-hosted-funnel-launch
LaunchSelf-hosted funnel launch is an agent skill that takes a funnel from an empty install to published on infrastructure you control, using the Autonnel funnel builder, which is licensed Apache-2.0. The result covers a landing page, checkout, a
Self-hosted
- G

get-convex/convex-backend
LaunchConvex is an open-source reactive database for web app developers. It combines a database, a place to write server functions in pure TypeScript, and client libraries that keep the app's data live, so screens update as the data changes. Beca
Self-hosted
About polars-bio

polars-bio
Performs genomic interval overlap, nearest, merge, coverage
polars-bio is an agent skill for genomic interval arithmetic and bioinformatics file input and output, using Polars and DataFusion. It covers overlap, nearest-neighbour, merge, coverage, complement and subtraction operations on Polars DataFrames, and reading or writing BED, VCF, BCF, BAM and CRAM files. The skill targets polars-bio 0.36.0, tested with Polars 1.44.2 on Python 3.13. The upstream package requires Polars 1.37.1 or newer, PyArrow from 23.0.1 up to but not including 25, DataFusion from 53 up to but not including 54, and polars-config-meta from 0.3.2 up to but not including 1. The skill advises keeping this environment separate from packages that need incompatible Arrow or DataFusion releases. It recommends checking new releases against the official release notes and package requirements. The examples that name files are templates, so you must substitute your own files and check their schemas. The synthetic interval example and small local format round-trip tests were run during the review. A pandas-compatible option is available if you install pandas 3 or newer alongside it.
- Price
- Free
- Made by
- k-dense-ai
- Category
- AI Skills
- Website
- github.com/k-dense-ai/scientific-agent-skills/polars-bio