Self-hosted alternatives to esm
5 self-hosted AI Skills apps to use instead, best rated first.
Top picks
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claude-to-deerflow
Launchclaude-to-deerflow is an agent skill that lets an assistant send messages and questions to a running DeerFlow instance through its HTTP API. DeerFlow is an AI agent platform built on LangGraph that orchestrates sub-agents for research, code
Self-hosted
- O

open-notebook
Launchopen-notebook is an agent skill for organising research with Open Notebook, a self-hosted alternative to NotebookLM. It arranges sources, notes and AI conversations into research notebooks. Sources can be PDFs, web pages, audio, video and O
Self-hosted
- R

Reactive Resume
LaunchReactive Resume is a free and open-source resume builder for writing resumes and cover letters, checking the work, and tracking job applications. You create a free account, import an existing resume or start from scratch, and see the finish
Open sourceSelf-hosted
- S

self-hosted-funnel-launch
LaunchSelf-hosted funnel launch is an agent skill that takes a funnel from an empty install to published on infrastructure you control, using the Autonnel funnel builder, which is licensed Apache-2.0. The result covers a landing page, checkout, a
Self-hosted
- G

get-convex/convex-backend
LaunchConvex is an open-source reactive database for web app developers. It combines a database, a place to write server functions in pure TypeScript, and client libraries that keep the app's data live, so screens update as the data changes. Beca
Self-hosted
About esm

esm
Uses the Biohub esm Python SDK for ESM3 protein generation, ESMC embeddings
esm is an agent skill for Biohub's esm Python SDK, which covers ESM3 protein generation, ESMC sequence embeddings and ESMFold2 all-atom structure prediction. It applies to local model inference and to Biohub's hosted services. Use it for ESM3 masked multimodal generation, for ESMC sequence representations, and for ESMFold2 folding. The former Forge platform has moved to biohub.ai, and the SDK's class names still contain the word Forge. The skill targets the released esm 3.4.1.post1 package, which it verified against the wheel and the current official documentation. It also separates related packages that people often confuse. fair-esm is Meta's separate, older ESM2, ESMFold and ESM-IF distribution. Both packages import as esm, so the skill says to install them in separate environments. The legacy esm.pretrained interface is not the Biohub ESMC interface, and Hugging Face Transformers has its own native ESMC implementation with different version requirements and output types. The skill's setup section explains how to choose a model. It is part of the k-dense-ai scientific agent skills repository on GitHub, which has about 49,600 stars.
- Price
- Free
- Made by
- k-dense-ai
- Category
- AI Skills
- Website
- github.com/k-dense-ai/scientific-agent-skills/esm